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ycxD [2019-08-28 08:55:56]
similar to transcriptional regulator ([SW|MocR/ GabR family])
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.6|Transcription factor/ other/ based on similarity]Gene
Coordinates
406,131 407,465
The protein
Protein family
[SW|MocR/ GabR family] [Pubmed|22020104][SW|class-I pyridoxal-phosphate-dependent aminotransferase family] (according to UniProt)[SW|Domains]
N-terminal DNA-binding helix-turn-helix motif; C-terminal domain is homologous to PLP-binding large domain of aminotransferases.[SW|Cofactors]
PLPStructure
[PDB|4MGR] ([protein|C7C36FAC0CE72226960FC7E8E016B8EC77AF1036|GabR], 27% identity) [pubmed|24127574]Biological materials
Mutant
BKE03560 ([gene|3A756A845ADA88DA569FA9A1B484DA43A28C6F4D|ycxD]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE03560 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGCCTTCTCCCCCTGTTT, downstream forward: _UP4_GGTGTCAAGCTGTTGATGAGBKK03560 ([gene|3A756A845ADA88DA569FA9A1B484DA43A28C6F4D|ycxD]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK03560 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGCCTTCTCCCCCTGTTT, downstream forward: _UP4_GGTGTCAAGCTGTTGATGAGReferences
11756427,22020104,24127574